Varaico: Literature-Extracted Genetic Variants

LATS1

253 papers

RefSeq Summary

The protein encoded by this gene is a putative serine/threonine kinase that localizes to the mitotic apparatus and complexes with cell cycle controller CDC2 kinase in early mitosis. The protein is pho...

Pfam Domains

UBAaa 101–138UCSCUBA/TS-N domain

Pkinaseaa 705–866UCSCProtein kinase domain

Pkinaseaa 896–1010UCSCProtein kinase domain

Pkinase_Caa 1030–1080UCSCProtein kinase C terminal domain

Gene Aliases

HGNC Name

large tumor suppressor kinase 1

HGNC Alias Symbol

WARTS

Papers

RefSeq ID

Protein change

DNA change

1–12 of 545 variants

7 papers

NM_004690.4

p.R995C

c.2983C>T

6 papers

NM_004690.4

p.R96W

c.286C>T

5 papers

NM_004690.4

p.S94A

c.280T>G

5 papers

NM_004690.4

p.P237Q

c.710C>A

5 papers

NM_004690.4

p.T851I

c.2552C>T

4 papers

NM_004690.4

p.N471S

c.1412A>G

4 papers

NM_004690.4

p.E753Q

c.2257G>C

4 papers

NM_004690.4

p.D846A

c.2537A>C

4 papers

NM_004690.4

p.R1020T

c.3059G>C

3 papers

NM_004690.4

p.R96Q

c.287G>A

3 papers

NM_004690.4

p.Y277C

c.830A>G

3 papers

NM_004690.4

p.S278C

c.833C>G