Varaico: Literature-Extracted Genetic Variants

Gene:LEP
Variant:p.F113F

LEP

798 papers

RefSeq Summary

This gene encodes a protein that is secreted by white adipocytes into the circulation and plays a major role in the regulation of energy homeostasis. Circulating leptin binds to the leptin receptor in...

Pfam Domains

Leptinaa 23–167UCSCLeptin

Gene Aliases

HGNC Name

leptin

HGNC Previous Symbols

OBS; OB

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_000230.3
p.F113F
c.339C>T
Surrounding Variants
1 paper
NM_000230.3
p.F113L
c.339C>A
2 papers
NM_000230.3
p.F113L
c.339C>G
2 papers
NM_000230.3
p.S114T
c.340T>A
4 papers
NM_000230.3
p.S114A
c.340T>G
1 paper
NM_000230.3
p.S114C
c.341C>G
1 paper
NM_000230.3
p.F113L
c.337T>C
1 paper
NM_000230.3
p.A112A
c.336C>T
1 paper
NM_000230.3
p.S114S
c.342T>A
1 paper
NM_000230.3
p.K115E
c.343A>G
2 papers
NM_000230.3
p.A112V
c.335C>T
1 paper
NM_000230.3
p.L111V
c.331C>G
1 paper
NM_000230.3
p.S116S
c.348C>T
UCSC Genome Browser·Imprint·Privacy·Terms·Feedback·Email Updates·

Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."