Varaico: Literature-Extracted Genetic Variants

Gene:MAP2K1
Variant:p.K57T

MAP2K1

1,996 papers

RefSeq Summary

The protein encoded by this gene is a member of the dual specificity protein kinase family, which acts as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular sign...

Pfam Domains

Pkinaseaa 46–127UCSCProtein kinase domain
Pkinaseaa 123–313UCSCProtein kinase domain

Gene Aliases

HGNC Name

mitogen-activated protein kinase kinase 1

HGNC Previous Symbol

PRKMK1

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
52 papers
NM_002755.4
p.K57T
c.170A>C
Surrounding Variants
6 papers
NM_002755.4
p.K57R
c.170A>G
4 papers
NM_002755.4
p.K57M
c.170A>T
1 paper
NM_002755.4
p.K57_Q58delins
c.170_172delinsGAT
6 papers
NM_002755.4
p.K57Q
c.169A>C
75 papers
NM_002755.4
p.K57E
c.169A>G
2 papers
NM_002755.4
p.K57*
c.169A>T
6 papers
NM_002755.4
p.Q58del1
c.172_173delCAG
8 papers
NM_002755.4
p.K57_E62del0
c.171_185del15
237 papers
NM_002755.4
p.K57N
c.171G>C
1 paper
NM_002755.4
p.Q58insFs
c.172dupC
1 paper
NM_002755.4
p.K57_Q58ins6
c.171_172ins18
243 papers
NM_002755.4
p.K57N
c.171G>T
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."