Varaico: Literature-Extracted Genetic Variants

Gene:MAP2K1
Variant:p.E62del1

MAP2K1

1,996 papers

RefSeq Summary

The protein encoded by this gene is a member of the dual specificity protein kinase family, which acts as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular sign...

Pfam Domains

Pkinaseaa 46–127UCSCProtein kinase domain
Pkinaseaa 123–313UCSCProtein kinase domain

Gene Aliases

HGNC Name

mitogen-activated protein kinase kinase 1

HGNC Previous Symbol

PRKMK1

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
4 papers
NM_002755.4
p.E62del1
c.184_185delGAA
Surrounding Variants
3 papers
NM_002755.4
p.G61G
c.183A>C
2 papers
NM_002755.4
p.G61G
c.183A>T
1 paper
NM_002755.4
p.G61R
c.181G>A
2 papers
NM_002755.4
p.E62K
c.184G>A
2 papers
NM_002755.4
p.E62*
c.184G>T
2 papers
NM_002755.4
p.G61_D65del5
c.181_194del15
1 paper
NM_002755.4
p.E62A
c.185A>C
1 paper
NM_002755.4
p.E62G
c.185A>G
9 papers
NM_002755.4
p.V60E
c.179T>A
2 papers
NM_002755.4
p.V60G
c.179T>G
1 paper
NM_002755.4
p.L63_D67del0
c.187_201del15
6 papers
NM_002755.4
p.V60M
c.178G>A
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."