Varaico: Literature-Extracted Genetic Variants

MED12

1,019 papers

RefSeq Summary

The initiation of transcription is controlled in part by a large protein assembly known as the preinitiation complex. A component of this preinitiation complex is a 1.2 MDa protein aggregate called Me...

Pfam Domains

Med12aa 104–161UCSCTranscription mediator complex subunit Med12

Med12-LCEWAVaa 286–757UCSCEukaryotic Mediator 12 subunit domain

Med12-PQLaa 1819–2022UCSCEukaryotic Mediator 12 catenin-binding domain

Gene Aliases

HGNC Name

mediator complex subunit 12

HGNC Previous Symbols

TNRC11; FGS1

Papers

RefSeq ID

Protein change

DNA change

1–12 of 1777 variants

132 papers

NM_005120.3

p.G44D

c.131G>A

98 papers

NM_005120.3

p.G44S

c.130G>A

79 papers

NM_005120.3

p.G44C

c.130G>T

71 papers

NM_005120.3

p.G44V

c.131G>T

61 papers

NM_005120.3

p.R961W

c.2881C>T

58 papers

NM_005120.3

p.G44R

c.130G>C

57 papers

NM_005120.3

p.G44A

c.131G>C

52 papers

NM_005120.3

p.L36R

c.107T>G

48 papers

NM_005120.3

p.Q43P

c.128A>C

47 papers

NM_005120.3

p.N1007S

c.3020A>G

32 papers

NM_005120.3

p.R1148H

c.3443G>A

26 papers

NM_005120.3

p.L1224F

c.3670C>T