Varaico: Literature-Extracted Genetic Variants

MET

3,492 papers

RefSeq Summary

This gene encodes a member of the receptor tyrosine kinase family of proteins and the product of the proto-oncogene MET. The encoded preproprotein is proteolytically processed to generate alpha and be...

Pfam Domains

Semaaa 317–493UCSCSema domain

PSIaa 519–562UCSCPlexin repeat

TIGaa 563–654UCSCIPT/TIG domain

TIGaa 657–739UCSCIPT/TIG domain

TIGaa 742–830UCSCIPT/TIG domain

PK_Tyr_Ser-Thraa 1078–1337UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

MET proto-oncogene, receptor tyrosine kinase

HGNC Alias Symbols

HGFR; RCCP2; DFNB97

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000245.4

p.G1095V

c.3284G>T

Surrounding Variants

1 paper

NM_000245.4

p.G1095E

c.3284G>A

1 paper

NM_000245.4

p.G1095R

c.3283G>A

1 paper

NM_000245.4

p.G1095R

c.3283G>C

1 paper

NM_000245.4

p.G1095G

c.3285G>T

1 paper

NM_000245.4

p.G1095_T1096Fs

c.3285_3286delinsCFs

5 papers

NM_000245.4

p.T1096S

c.3286A>T

26 papers

NM_000245.4

p.H1094R

c.3281A>G

NM_001127500.3

p.H1112R

c.3335A>G

6 papers

NM_000245.4

p.H1094L

c.3281A>T

5 papers

NM_000245.4

p.T1096S

c.3287C>G

2 papers

NM_000245.4

p.T1096I

c.3287C>T

1 paper

NM_000245.4

p.H1094N

c.3280C>A

4 papers

NM_000245.4

p.H1094D

c.3280C>G