Varaico: Literature-Extracted Genetic Variants

MET

3,492 papers

RefSeq Summary

This gene encodes a member of the receptor tyrosine kinase family of proteins and the product of the proto-oncogene MET. The encoded preproprotein is proteolytically processed to generate alpha and be...

Pfam Domains

Semaaa 317–493UCSCSema domain

PSIaa 519–562UCSCPlexin repeat

TIGaa 563–654UCSCIPT/TIG domain

TIGaa 657–739UCSCIPT/TIG domain

TIGaa 742–830UCSCIPT/TIG domain

PK_Tyr_Ser-Thraa 1078–1337UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

MET proto-oncogene, receptor tyrosine kinase

HGNC Alias Symbols

HGFR; RCCP2; DFNB97

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_000245.4

p.H1106Y

c.3316C>T

Surrounding Variants

2 papers

NM_000245.4

p.H1106N

c.3316C>A

1 paper

NM_000245.4

p.H1106fs

c.3316_3317fs

10 papers

NM_000245.4

p.H1106D

c.3316C>G

NM_001127500.3

p.H1124D

c.3370C>G

2 papers

NM_000245.4

p.I1105M

c.3315T>G

2 papers

NM_000245.4

p.H1106Q

c.3318C>A

2 papers

NM_000245.4

p.H1106Q

c.3318C>G

1 paper

NM_000245.4

p.I1105N

c.3314T>A

1 paper

NM_000245.4

p.I1105S

c.3314T>G

1 paper

NM_000245.4

p.I1105L

c.3313A>C

1 paper

NM_000245.4

p.I1105F

c.3313A>T

1 paper

NM_000245.4

p.C1107S

c.3319T>A

2 papers

NM_000245.4

p.C1107R

c.3319T>C