Varaico: Literature-Extracted Genetic Variants

MET

3,492 papers

RefSeq Summary

This gene encodes a member of the receptor tyrosine kinase family of proteins and the product of the proto-oncogene MET. The encoded preproprotein is proteolytically processed to generate alpha and be...

Pfam Domains

Semaaa 317–493UCSCSema domain

PSIaa 519–562UCSCPlexin repeat

TIGaa 563–654UCSCIPT/TIG domain

TIGaa 657–739UCSCIPT/TIG domain

TIGaa 742–830UCSCIPT/TIG domain

PK_Tyr_Ser-Thraa 1078–1337UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

MET proto-oncogene, receptor tyrosine kinase

HGNC Alias Symbols

HGFR; RCCP2; DFNB97

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_000245.4

p.Y1194H

c.3580T>C

Surrounding Variants

1 paper

NM_000245.4

p.K1193N

c.3579A>C

2 papers

NM_000245.4

p.Y1194C

c.3581A>G

3 papers

NM_000245.4

p.Y1194F

c.3581A>T

1 paper

NM_000245.4

p.K1193N

c.3579A>T

1 paper

NM_000245.4

p.K1193I

c.3578A>T

1 paper

NM_000245.4

p.K1193E

c.3577A>G

4 papers

NM_000245.4

p.L1195I

c.3583C>A

NM_001127500.3

p.L1213I

c.3637C>A

62 papers

NM_000245.4

p.L1195V

c.3583C>G

NM_001127500.3

p.L1213V

c.3637C>G

17 papers

NM_000245.4

p.L1195F

c.3583C>T

NM_001127500.3

p.L1213F

c.3637C>T

7 papers

NM_000245.4

p.M1192I

c.3576G>A

6 papers

NM_000245.4

p.M1192I

c.3576G>C

6 papers

NM_000245.4

p.M1192I

c.3576G>T