Varaico: Literature-Extracted Genetic Variants

MET

3,492 papers

RefSeq Summary

This gene encodes a member of the receptor tyrosine kinase family of proteins and the product of the proto-oncogene MET. The encoded preproprotein is proteolytically processed to generate alpha and be...

Pfam Domains

Semaaa 317–493UCSCSema domain

PSIaa 519–562UCSCPlexin repeat

TIGaa 563–654UCSCIPT/TIG domain

TIGaa 657–739UCSCIPT/TIG domain

TIGaa 742–830UCSCIPT/TIG domain

PK_Tyr_Ser-Thraa 1078–1337UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

MET proto-oncogene, receptor tyrosine kinase

HGNC Alias Symbols

HGFR; RCCP2; DFNB97

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000245.4

p.V1201F

c.3601G>T

Surrounding Variants

1 paper

NM_000245.4

p.V1201I

c.3601G>A

1 paper

NM_000245.4

p.V1201L

c.3601G>C

6 papers

NM_000245.4

p.F1200L

c.3600T>A

1 paper

NM_000245.4

p.V1201A

c.3602T>C

6 papers

NM_000245.4

p.F1200L

c.3600T>G

1 paper

NM_000245.4

p.H1202fs

c.3604_3605fs

1 paper

NM_000245.4

p.H1202Y

c.3604C>T

23 papers

NM_000245.4

p.F1200I

c.3598T>A

6 papers

NM_000245.4

p.F1200L

c.3598T>C

3 papers

NM_000245.4

p.F1200V

c.3598T>G

1 paper

NM_000245.4

p.H1202R

c.3605A>G

1 paper

NM_000245.4

p.H1202L

c.3605A>T