Varaico: Literature-Extracted Genetic Variants

MET

3,492 papers

RefSeq Summary

This gene encodes a member of the receptor tyrosine kinase family of proteins and the product of the proto-oncogene MET. The encoded preproprotein is proteolytically processed to generate alpha and be...

Pfam Domains

Semaaa 317–493UCSCSema domain

PSIaa 519–562UCSCPlexin repeat

TIGaa 563–654UCSCIPT/TIG domain

TIGaa 657–739UCSCIPT/TIG domain

TIGaa 742–830UCSCIPT/TIG domain

PK_Tyr_Ser-Thraa 1078–1337UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

MET proto-oncogene, receptor tyrosine kinase

HGNC Alias Symbols

HGFR; RCCP2; DFNB97

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000245.4

p.K1219E

c.3655A>G

Surrounding Variants

1 paper

NM_000245.4

p.K1219M

c.3656A>T

1 paper

NM_000245.4

p.K1219N

c.3657G>C

1 paper

NM_000245.4

p.K1219N

c.3657G>T

1 paper

NM_000245.4

p.V1218A

c.3653T>C

14 papers

NM_000245.4

p.V1220I

c.3658G>A

NM_001127500.3

p.V1238I

c.3712G>A

1 paper

NM_000245.4

p.V1218I

c.3652G>A

2 papers

NM_000245.4

p.V1220L

c.3658G>C

1 paper

NM_000245.4

p.V1218L

c.3652G>C

1 paper

NM_000245.4

p.V1218F

c.3652G>T

1 paper

NM_000245.4

p.V1220A

c.3659T>C

1 paper

NM_000245.4

p.T1217K

c.3650C>A

1 paper

NM_000245.4

p.T1217R

c.3650C>G