Varaico: Literature-Extracted Genetic Variants

MLKL

113 papers

RefSeq Summary

This gene belongs to the protein kinase superfamily. The encoded protein contains a protein kinase-like domain; however, is thought to be inactive because it lacks several residues required for activi...

Pfam Domains

MLKL_Naa 4–146UCSCMixed lineage kinase domain-like N-terminal domain

PK_Tyr_Ser-Thraa 209–466UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

mixed lineage kinase domain like pseudokinase

HGNC Alias Symbol

FLJ34389

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

4 papers

NM_152649.4

p.D369_R370delFs

c.1107_1110del4

Surrounding Variants

2 papers

NM_152649.4

p.D369fs

c.1105_1106fs

1 paper

NM_152649.4

p.D369A

c.1106A>C

1 paper

NM_152649.4

p.S373A

c.1117T>G

3 papers

NM_152649.4

p.D369fs

c.1105_1106fs

1 paper

NM_152649.4

p.T368fs

c.1102_1103fs

1 paper

NM_152649.4

p.T374A

c.1120A>G

1 paper

NM_152649.4

p.E366A

c.1097A>C

1 paper

NM_152649.4

p.T364M

c.1091C>T

6 papers

NM_152649.4

p.S358A

c.1072T>G

6 papers

NM_152649.4

p.T357A

c.1069A>G

1 paper

NM_152649.4

p.T355A

c.1063A>G

1 paper

NM_152649.4

p.E351Q

c.1051G>C