Varaico: Literature-Extracted Genetic Variants

Gene:MPL
Variant:p.L510P

MPL

1,557 papers

RefSeq Summary

In 1990 an oncogene, v-mpl, was identified from the murine myeloproliferative leukemia virus that was capable of immortalizing bone marrow hematopoietic cells from different lineages. In 1992 the huma...

Pfam Domains

EpoR_lig-bindaa 25–128UCSCErythropoietin receptor, ligand binding

Gene Aliases

HGNC Name

MPL proto-oncogene, thrombopoietin receptor

HGNC Alias Symbols

CD110; TPOR; THPOR

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
33 papers
NM_005373.3
p.L510P
c.1529T>C
Surrounding Variants
1 paper
NM_005373.3
p.L510fs
c.1528_1529fs
1 paper
NM_005373.3
p.L510fs
c.1528_1529fs
4 papers
NM_005373.3
p.L513del1
c.1537_1538delCTG
1 paper
NM_005373.3
p.G509V
c.1526G>T
10 papers
NM_005373.3
p.G509C
c.1525G>T
1 paper
NM_005373.3
p.L512L
c.1534C>T
1 paper
NM_005373.3
p.L508Q
c.1523T>A
1 paper
NM_005373.3
p.L512L
c.1536G>A
1 paper
NM_005373.3
p.L513_R514ins4
c.1539_1540ins12
1 paper
NM_005373.3
p.V507A
c.1520T>C
1 paper
NM_005373.3
p.V507G
c.1520T>G
6 papers
NM_005373.3
p.V507I
c.1519G>A
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