Varaico: Literature-Extracted Genetic Variants

Gene:MPL
Variant:p.A519A

MPL

1,557 papers

RefSeq Summary

In 1990 an oncogene, v-mpl, was identified from the murine myeloproliferative leukemia virus that was capable of immortalizing bone marrow hematopoietic cells from different lineages. In 1992 the huma...

Pfam Domains

EpoR_lig-bindaa 25–128UCSCErythropoietin receptor, ligand binding

Gene Aliases

HGNC Name

MPL proto-oncogene, thrombopoietin receptor

HGNC Alias Symbols

CD110; TPOR; THPOR

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_005373.3
p.A519A
c.1557A>G
Surrounding Variants
1 paper
NM_005373.3
p.A519G
c.1556C>G
22 papers
NM_005373.3
p.A519V
c.1556C>T
2 papers
NM_005373.3
p.H520P
c.1559A>C
1 paper
NM_005373.3
p.H520R
c.1559A>G
32 papers
NM_005373.3
p.A519T
c.1555G>A
1 paper
NM_005373.3
p.A519insFs
c.1555_1556ins31
1 paper
NM_005373.3
p.A519fs
c.1555_1556fs
1 paper
NM_005373.3
p.Y521C
c.1562A>G
1 paper
NM_005373.3
p.P518S
c.1552C>T
1 paper
NM_005373.3
p.F517L
c.1551T>A
1 paper
NM_005373.3
p.F517L
c.1551T>G
1 paper
NM_005373.3
p.R522G
c.1564A>G
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."