Varaico: Literature-Extracted Genetic Variants

MST1R

329 papers

RefSeq Summary

This gene encodes a cell surface receptor for macrophage-stimulating protein (MSP) with tyrosine kinase activity. The mature form of this protein is a heterodimer of disulfide-linked alpha and beta su...

Pfam Domains

Semaaa 321–504UCSCSema domain

PSIaa 526–568UCSCPlexin repeat

TIGaa 569–674UCSCIPT/TIG domain

TIGaa 684–766UCSCIPT/TIG domain

TIGaa 770–859UCSCIPT/TIG domain

PK_Tyr_Ser-Thraa 1082–1341UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

macrophage stimulating 1 receptor

HGNC Previous Symbols

RON; PTK8; SEA

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002447.4

p.R1263*

c.3787A>T

Surrounding Variants

1 paper

NM_002447.4

p.A1255V

c.3764C>T

11 papers

NM_002447.4

p.M1254T

c.3761T>C

1 paper

NM_002447.4

p.R1248C

c.3742C>T

1 paper

NM_002447.4

p.H1244L

c.3731A>T

1 paper

NM_002447.4

p.V1241I

c.3721G>A

1 paper

NM_002447.4

p.S1240R

c.3720T>G

1 paper

NM_002447.4

p.S1240R

c.3720T>A

1 paper

NM_002447.4

p.S1240R

c.3718A>C

1 paper

NM_002447.4

p.R1236T

c.3707G>C

6 papers

NM_002447.4

p.D1232V

c.3695A>T

2 papers

NM_002447.4

p.D1232H

c.3694G>C

1 paper

NM_002447.4

p.D1232N

c.3694G>A