Varaico: Literature-Extracted Genetic Variants

MYC

2,231 papers

RefSeq Summary

This gene is a proto-oncogene and encodes a nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. The encoded protein forms a heterodimer with the ...

Pfam Domains

Myc_Naa 17–360UCSCMyc amino-terminal region

HLHaa 370–422UCSCHelix-loop-helix DNA-binding domain

Myc-LZaa 423–453UCSCMyc leucine zipper domain

Gene Aliases

HGNC Name

MYC proto-oncogene, bHLH transcription factor

HGNC Alias Symbols

c-Myc; bHLHe39; MYCC

Papers

RefSeq ID

Protein change

DNA change

1–12 of 1329 variants

33 papers

NM_002467.6

p.S161L

c.482C>T

30 papers

NM_002467.6

p.P74L

c.221C>T

26 papers

NM_002467.6

p.N26S

c.77A>G

25 papers

NM_002467.6

p.A59V

c.176C>T

21 papers

NM_002467.6

p.P57S

c.169C>T

21 papers

NM_002467.6

p.T73I

c.218C>T

20 papers

NM_002467.6

p.P72S

c.214C>T

16 papers

NM_002467.6

p.T73A

c.217A>G

15 papers

NM_002467.6

p.Q48del1

c.142_143delCAG

15 papers

NM_002467.6

p.E54D

c.162G>C

14 papers

NM_002467.6

p.E54D

c.162G>T

14 papers

NM_002467.6

p.T73N

c.218C>A