Varaico: Literature-Extracted Genetic Variants

MYD88

369 papers

RefSeq Summary

This gene encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. This protein functions as an essential signal transducer in the interleukin-1 and To...

Pfam Domains

Deathaa 30–108UCSCDeath domain

Deathaa 43–121UCSCDeath domain

TIR_2aa 163–292UCSCTIR domain

Gene Aliases

HGNC Name

MYD88 innate immune signal transduction adaptor

HGNC Previous Names

myeloid differentiation primary response gene (88); myeloid differentiation primary response 88

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002468.5

p.W47C

c.141G>C

Surrounding Variants

1 paper

NM_002468.5

p.W47C

c.141G>T

1 paper

NM_002468.5

p.T48delFs

c.142_143delAC

1 paper

NM_002468.5

p.D46delFs

c.137_138delAC

1 paper

NM_002468.5

p.A49A

c.147G>A

1 paper

NM_002468.5

p.A45G

c.134C>G

1 paper

NM_002468.5

p.A45_T48delFs

c.135_142del8

1 paper

NM_002468.5

p.A45S

c.133G>T

1 paper

NM_002468.5

p.A44A

c.132G>C

11 papers

NM_002468.5

p.E52del1

c.154_155delGAG

2 papers

NM_002468.5

p.A44T

c.130G>A

1 paper

NM_002468.5

p.E52K

c.154G>A

1 paper

NM_002468.5

p.V43G

c.128T>G