Varaico: Literature-Extracted Genetic Variants

MYD88

369 papers

RefSeq Summary

This gene encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. This protein functions as an essential signal transducer in the interleukin-1 and To...

Pfam Domains

Deathaa 30–108UCSCDeath domain

Deathaa 43–121UCSCDeath domain

TIR_2aa 163–292UCSCTIR domain

Gene Aliases

HGNC Name

MYD88 innate immune signal transduction adaptor

HGNC Previous Names

myeloid differentiation primary response gene (88); myeloid differentiation primary response 88

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002468.5

p.D55V

c.164A>T

Surrounding Variants

1 paper

NM_002468.5

p.F56C

c.167T>G

1 paper

NM_002468.5

p.E53D

c.159G>C

1 paper

NM_002468.5

p.E57delFs

c.170delA

1 paper

NM_002468.5

p.E53V

c.158A>T

1 paper

NM_002468.5

p.E52K

c.154G>A

11 papers

NM_002468.5

p.E52del1

c.154_155delGAG

1 paper

NM_002468.5

p.A49A

c.147G>A

1 paper

NM_002468.5

p.Q63*

c.187C>T

1 paper

NM_002468.5

p.W47C

c.141G>C

1 paper

NM_002468.5

p.W47C

c.141G>T

1 paper

NM_002468.5

p.T48delFs

c.142_143delAC

1 paper

NM_002468.5

p.L64_A68delFs

c.190_202del13