Varaico: Literature-Extracted Genetic Variants

MYD88

369 papers

RefSeq Summary

This gene encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. This protein functions as an essential signal transducer in the interleukin-1 and To...

Pfam Domains

Deathaa 30–108UCSCDeath domain

Deathaa 43–121UCSCDeath domain

TIR_2aa 163–292UCSCTIR domain

Gene Aliases

HGNC Name

MYD88 innate immune signal transduction adaptor

HGNC Previous Names

myeloid differentiation primary response gene (88); myeloid differentiation primary response 88

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002468.5

p.R88L

c.263G>T

Surrounding Variants

1 paper

NM_002468.5

p.L89V

c.265C>G

1 paper

NM_002468.5

p.V86L

c.256G>C

1 paper

NM_002468.5

p.V86L

c.256G>T

2 papers

NM_002468.5

p.S85P

c.253T>C

1 paper

NM_002468.5

p.A84V

c.251C>T

1 paper

NM_002468.5

p.L93V

c.277C>G

10 papers

NM_002468.5

p.L93P

c.278T>C

1 paper

NM_002468.5

p.P82L

c.245C>T

1 paper

NM_002468.5

p.R81S

c.241C>A

1 paper

NM_002468.5

p.R81C

c.241C>T

1 paper

NM_002468.5

p.G97S

c.289G>A

1 paper

NM_002468.5

p.G80_R81del2

c.238_242del6