Varaico: Literature-Extracted Genetic Variants

MYH7

2,286 papers

RefSeq Summary

Muscle myosin is a hexameric protein containing 2 heavy chain subunits, 2 alkali light chain subunits, and 2 regulatory light chain subunits. This gene encodes the beta (or slow) heavy chain subunit o...

Pfam Domains

Myosin_Naa 32–76UCSCMyosin N-terminal SH3-like domain

Myosin_headaa 87–766UCSCMyosin head (motor domain)

Myosin_tail_1aa 843–1924UCSCMyosin tail

Gene Aliases

HGNC Name

myosin heavy chain 7

HGNC Previous Symbols

CMH1; MPD1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

3 papers

NM_000257.4

p.T449S

c.1345A>T

Surrounding Variants

2 papers

NM_000257.4

p.T449I

c.1346C>T

2 papers

NM_000257.4

p.T449S

c.1346C>G

4 papers

NM_000257.4

p.T449N

c.1346C>A

1 paper

NM_000257.4

p.E448Q

c.1342G>C

2 papers

NM_000257.4

p.E448K

c.1342G>A

3 papers

NM_000257.4

p.K450E

c.1348A>G

2 papers

NM_000257.4

p.K450T

c.1349A>C

5 papers

NM_000257.4

p.K450N

c.1350G>T

5 papers

NM_000257.4

p.K450N

c.1350G>C

1 paper

NM_000257.4

p.Q451K

c.1351C>A

1 paper

NM_000257.4

p.Q451P

c.1352A>C

5 papers

NM_000257.4

p.T446P

c.1336A>C