Varaico: Literature-Extracted Genetic Variants

NCOR2

573 papers

RefSeq Summary

This gene encodes a nuclear receptor co-repressor that mediates transcriptional silencing of certain target genes. The encoded protein is a member of a family of thyroid hormone- and retinoic acid rec...

Pfam Domains

GPS2_interactaa 141–229UCSCG-protein pathway suppressor 2-interacting domain

Myb_DNA-bindingaa 428–473UCSCMyb-like DNA-binding domain

Myb_DNA-bindingaa 611–656UCSCMyb-like DNA-binding domain

Gene Aliases

HGNC Name

nuclear receptor corepressor 2

HGNC Alias Symbols

SMRT; SMRTE; TRAC-1; CTG26; TNRC14

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

5 papers

NM_006312.6

p.R243W

c.727C>T

Surrounding Variants

6 papers

NM_006312.6

p.R243Q

c.728G>A

1 paper

NM_006312.6

p.R235_K236Splc

c.706-1G>C

1 paper

NM_006312.6

p.Q251K

c.751C>A

1 paper

NM_006312.6

p.P255L

c.764C>T

1 paper

NM_006312.6

p.P255R

c.764C>G

1 paper

NM_006312.6

p.Q259P

c.776A>C

1 paper

NM_006312.6

p.P260L

c.779C>T

2 papers

NM_006312.6

p.D262N

c.784G>A

1 paper

NM_006312.6

p.D262G

c.785A>G

1 paper

NM_006312.6

p.Q265H

c.795G>T

1 paper

NM_006312.6

p.Q265H

c.795G>C

1 paper

NM_006312.6

p.P255_H267delFs

c.765_799del35