Varaico: Literature-Extracted Genetic Variants

NEIL1

157 papers

RefSeq Summary

This gene is a member of the Nei endonuclease VIII-like gene family which encodes DNA glycosylases. The encoded enzyme participates in the DNA repair pathway by initiating base excision repair by remo...

Pfam Domains

Fapy_DNA_glycoaa 1–123UCSCFormamidopyrimidine-DNA glycosylase N-terminal domain

Neil1-DNA_bindaa 252–290UCSCEndonuclease VIII-like 1, DNA bind

Gene Aliases

HGNC Name

nei like DNA glycosylase 1

HGNC Alias Symbols

FLJ22402; hFPG1; NEI1; FPG1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

8 papers

NM_024608.4

p.R145Splc

c.434+2T>C

NM_001256552.1

p.R231Splc

c.692+2T>C

Surrounding Variants

11 papers

NM_024608.4

p.C136R

c.406T>C

1 paper

NM_024608.4

p.A111fs

c.331_332fs

2 papers

NM_024608.4

p.L110_A111insFs

c.330_331ins4

1 paper

NM_024608.4

p.R109_L110insFs

c.327_328ins4

1 paper

NM_024608.4

p.R109W

c.325C>T

1 paper

NM_024608.4

p.P108L

c.323C>T

1 paper

NM_024608.4

p.P105L

c.314C>T

2 papers

NM_024608.4

p.P105insFs

c.314dupC

1 paper

NM_024608.4

p.T103A

c.307A>G

4 papers

NM_024608.4

p.R95G

c.283C>G

1 paper

NM_024608.4

p.R90C

c.268C>T

26 papers

NM_024608.4

p.G83D

c.248G>A

NM_001256552.1

p.G169D

c.506G>A