Varaico: Literature-Extracted Genetic Variants

NOS2

843 papers

RefSeq Summary

Nitric oxide is a reactive free radical which acts as a biologic mediator in several processes, including neurotransmission and antimicrobial and antitumoral activities. This gene encodes a nitric oxi...

Pfam Domains

NO_synthaseaa 135–497UCSCNitric oxide synthase, oxygenase domain

Flavodoxin_1aa 541–672UCSCFlavodoxin

FAD_binding_1aa 725–947UCSCFAD binding domain

NAD_binding_1aa 979–1093UCSCOxidoreductase NAD-binding domain

Gene Aliases

HGNC Name

nitric oxide synthase 2

HGNC Previous Symbol

NOS2A

Papers

RefSeq ID

Protein change

DNA change

1–12 of 323 variants

110 papers

NM_000625.4

p.K298N

c.894G>T

74 papers

NM_000625.4

p.A262A

c.786T>C

68 papers

NM_000625.4

p.S608L

c.1823C>T

20 papers

NM_000625.4

p.I391I

c.1173C>T

11 papers

NM_000625.4

p.T77T

c.231C>T

11 papers

NM_000625.4

p.L342L

c.1026G>T

7 papers

NM_000625.4

p.R221W

c.661C>T

6 papers

NM_000625.4

p.S50S

c.150C>T

5 papers

NM_000625.4

p.G93A

c.278G>C

5 papers

NM_000625.4

p.L318L

c.954C>G

4 papers

NM_000625.4

p.K696R

c.2087A>G

3 papers

NM_000625.4

p.P297S

c.889C>T