Varaico: Literature-Extracted Genetic Variants

NR3C1

1,293 papers

RefSeq Summary

This gene encodes glucocorticoid receptor, which can function both as a transcription factor that binds to glucocorticoid response elements in the promoters of glucocorticoid responsive genes to activ...

Pfam Domains

GCRaa 26–401UCSCGlucocorticoid receptor

zf-C4aa 419–488UCSCDouble treble clef zinc finger, C4 type

Hormone_recepaa 549–741UCSCLigand-binding domain of nuclear hormone receptor

Gene Aliases

HGNC Name

nuclear receptor subfamily 3 group C member 1

HGNC Previous Symbol

GRL

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

23 papers

NM_000176.3

p.F737L

c.2211C>A

Surrounding Variants

23 papers

NM_000176.3

p.F737L

c.2211C>G

1 paper

NM_000176.3

p.F737S

c.2210T>C

4 papers

NM_000176.3

p.F737V

c.2209T>G

25 papers

NM_000176.3

p.F737L

c.2209T>C

4 papers

NM_000176.3

p.C736S

c.2207G>C

1 paper

NM_000176.3

p.T739A

c.2215A>G

3 papers

NM_000176.3

p.C736G

c.2206T>G

4 papers

NM_000176.3

p.C736S

c.2206T>A

1 paper

NM_000176.3

p.F740_L741insCC

c.2218_2222ins6

2 papers

NM_000176.3

p.Y735F

c.2204A>T

2 papers

NM_000176.3

p.Y735S

c.2204A>C

1 paper

NM_000176.3

p.L741F

c.2223G>T