Varaico: Literature-Extracted Genetic Variants

NR3C1

1,293 papers

RefSeq Summary

This gene encodes glucocorticoid receptor, which can function both as a transcription factor that binds to glucocorticoid response elements in the promoters of glucocorticoid responsive genes to activ...

Pfam Domains

GCRaa 26–401UCSCGlucocorticoid receptor

zf-C4aa 419–488UCSCDouble treble clef zinc finger, C4 type

Hormone_recepaa 549–741UCSCLigand-binding domain of nuclear hormone receptor

Gene Aliases

HGNC Name

nuclear receptor subfamily 3 group C member 1

HGNC Previous Symbol

GRL

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000176.3

p.Q713*

c.2137C>T

Surrounding Variants

3 papers

NM_000176.3

p.W712S

c.2135G>C

1 paper

NM_000176.3

p.R714W

c.2140C>T

1 paper

NM_000176.3

p.R714L

c.2141G>T

2 papers

NM_000176.3

p.R714P

c.2141G>C

21 papers

NM_000176.3

p.R714Q

c.2141G>A

1 paper

NM_000176.3

p.N711S

c.2132A>G

4 papers

NM_000176.3

p.Q710*

c.2128C>T

1 paper

NM_000176.3

p.Q710K

c.2128C>A

1 paper

NM_000176.3

p.Y716C

c.2147A>G

2 papers

NM_000176.3

p.Y716S

c.2147A>C

1 paper

NM_000176.3

p.S709N

c.2126G>A

1 paper

NM_000176.3

p.S708A

c.2122T>G