Varaico: Literature-Extracted Genetic Variants

NR3C1

1,293 papers

RefSeq Summary

This gene encodes glucocorticoid receptor, which can function both as a transcription factor that binds to glucocorticoid response elements in the promoters of glucocorticoid responsive genes to activ...

Pfam Domains

GCRaa 26–401UCSCGlucocorticoid receptor

zf-C4aa 419–488UCSCDouble treble clef zinc finger, C4 type

Hormone_recepaa 549–741UCSCLigand-binding domain of nuclear hormone receptor

Gene Aliases

HGNC Name

nuclear receptor subfamily 3 group C member 1

HGNC Previous Symbol

GRL

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000176.3

p.R569delins

c.1705_1706delinsAA

Surrounding Variants

3 papers

NM_000176.3

p.R569Q

c.1706G>A

1 paper

NM_000176.3

p.R569W

c.1705C>T

1 paper

NM_000176.3

p.G568W

c.1702G>T

5 papers

NM_000176.3

p.V571M

c.1711G>A

33 papers

NM_000176.3

p.V571A

c.1712T>C

4 papers

NM_000176.3

p.G567A

c.1700G>C

3 papers

NM_000176.3

p.M565R

c.1694T>G

1 paper

NM_000176.3

p.M565K

c.1694T>A

2 papers

NM_000176.3

p.A573E

c.1718C>A

2 papers

NM_000176.3

p.A574V

c.1721C>T

2 papers

NM_000176.3

p.V575M

c.1723G>A

17 papers

NM_000176.3

p.V575G

c.1724T>G