Varaico: Literature-Extracted Genetic Variants

NR3C1

1,293 papers

RefSeq Summary

This gene encodes glucocorticoid receptor, which can function both as a transcription factor that binds to glucocorticoid response elements in the promoters of glucocorticoid responsive genes to activ...

Pfam Domains

GCRaa 26–401UCSCGlucocorticoid receptor

zf-C4aa 419–488UCSCDouble treble clef zinc finger, C4 type

Hormone_recepaa 549–741UCSCLigand-binding domain of nuclear hormone receptor

Gene Aliases

HGNC Name

nuclear receptor subfamily 3 group C member 1

HGNC Previous Symbol

GRL

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000176.3

p.C223fs

c.667_668fs

Surrounding Variants

10 papers

NM_000176.3

p.S226A

c.676T>G

1 paper

NM_000176.3

p.S226P

c.676T>C

3 papers

NM_000176.3

p.S226F

c.677C>T

1 paper

NM_000176.3

p.P227L

c.680C>T

4 papers

NM_000176.3

p.A229T

c.685G>A

1 paper

NM_000176.3

p.A229V

c.686C>T

1 paper

NM_000176.3

p.L217L

c.649C>T

1 paper

NM_000176.3

p.D216E

c.648C>A

1 paper

NM_000176.3

p.N222_E231del10

c.664_692del30

2 papers

NM_000176.3

p.S215*

c.644C>G

1 paper

NM_000176.3

p.D232G

c.695A>G

1 paper

NM_000176.3

p.D232A

c.695A>C