Varaico: Literature-Extracted Genetic Variants

ODC1

160 papers

RefSeq Summary

This gene encodes the rate-limiting enzyme of the polyamine biosynthesis pathway which catalyzes ornithine to putrescine. The activity level for the enzyme varies in response to growth-promoting stimu...

Pfam Domains

Orn_DAP_Arg_deCaa 40–387UCSCPyridoxal-dependent decarboxylase, C-terminal sheet domain

Orn_Arg_deC_Naa 45–281UCSCPyridoxal-dependent decarboxylase, pyridoxal binding domain

Gene Aliases

HGNC Name

ornithine decarboxylase 1

Papers

RefSeq ID

Protein change

DNA change

1–12 of 172 variants

7 papers

NM_002539.3

p.E106K

c.316G>A

6 papers

NM_002539.3

p.K69R

c.206A>G

6 papers

NM_002539.3

p.Q419*

c.1255C>T

5 papers

NM_002539.3

p.K448*

c.1342A>T

4 papers

NM_002539.3

p.G84R

c.250G>C

4 papers

NM_002539.3

p.G84R

c.250G>A

4 papers

NM_002539.3

p.W414fs

c.1240_1241fs

3 papers

NM_002539.3

p.E274A

c.821A>C

3 papers

NM_002539.3

p.C360S

c.1078T>A

3 papers

NM_002539.3

p.C360S

c.1079G>C

3 papers

NM_002539.3

p.W414Splc

c.1241+1G>T

3 papers

NM_002539.3

p.W414*

c.1241G>A