Varaico: Literature-Extracted Genetic Variants

ODC1

160 papers

RefSeq Summary

This gene encodes the rate-limiting enzyme of the polyamine biosynthesis pathway which catalyzes ornithine to putrescine. The activity level for the enzyme varies in response to growth-promoting stimu...

Pfam Domains

Orn_DAP_Arg_deCaa 40–387UCSCPyridoxal-dependent decarboxylase, C-terminal sheet domain

Orn_Arg_deC_Naa 45–281UCSCPyridoxal-dependent decarboxylase, pyridoxal binding domain

Gene Aliases

HGNC Name

ornithine decarboxylase 1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

6 papers

NM_002539.3

p.K69R

c.206A>G

Surrounding Variants

1 paper

NM_002539.3

p.K69K

c.207A>G

1 paper

NM_002539.3

p.C70S

c.208T>A

1 paper

NM_002539.3

p.C70S

c.209G>C

1 paper

NM_002539.3

p.A67S

c.199G>T

1 paper

NM_002539.3

p.A67T

c.199G>A

1 paper

NM_002539.3

p.R61H

c.182G>A

1 paper

NM_002539.3

p.K57R

c.170A>G

2 papers

NM_002539.3

p.A82A

c.246T>A

4 papers

NM_002539.3

p.G84R

c.250G>C

4 papers

NM_002539.3

p.G84R

c.250G>A

1 paper

NM_002539.3

p.L53insFs

c.158dupT

1 paper

NM_002539.3

p.G86R

c.256G>C