Varaico: Literature-Extracted Genetic Variants

OGG1

1,056 papers

RefSeq Summary

This gene encodes the enzyme responsible for the excision of 8-oxoguanine, a mutagenic base byproduct which occurs as a result of exposure to reactive oxygen. The action of this enzyme includes lyase ...

Pfam Domains

OGG_Naa 25–141UCSC8-oxoguanine DNA glycosylase, N-terminal domain

HhH-GPDaa 142–296UCSCHhH-GPD superfamily base excision DNA repair protein

HhH-GPDaa 142–299UCSCHhH-GPD superfamily base excision DNA repair protein

Gene Aliases

HGNC Name

8-oxoguanine DNA glycosylase

HGNC Alias Symbols

HMMH; HOGG1; OGH1; MUTM

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002542.6

p.F302S

c.905T>C

Surrounding Variants

1 paper

NM_002542.6

p.F302L

c.906T>A

1 paper

NM_002542.6

p.F302L

c.904T>C

1 paper

NM_002542.6

p.F302L

c.906T>G

1 paper

NM_002542.6

p.N301N

c.903C>T

6 papers

NM_002542.6

p.R304W

c.910C>T

1 paper

NM_002542.6

p.G300E

c.899G>A

1 paper

NM_002542.6

p.G300A

c.899G>C

1 paper

NM_002542.6

p.N301delFs

c.901delA

1 paper

NM_002542.6

p.G300Splc

c.899-2A>G

1 paper

NM_002542.6

p.L306L

c.916C>T

1 paper

NM_002542.6

p.G300Splc

c.898+140A>C

1 paper

NM_002542.6

p.W307*

c.920G>A