Varaico: Literature-Extracted Genetic Variants

OGG1

1,056 papers

RefSeq Summary

This gene encodes the enzyme responsible for the excision of 8-oxoguanine, a mutagenic base byproduct which occurs as a result of exposure to reactive oxygen. The action of this enzyme includes lyase ...

Pfam Domains

OGG_Naa 25–141UCSC8-oxoguanine DNA glycosylase, N-terminal domain

HhH-GPDaa 142–296UCSCHhH-GPD superfamily base excision DNA repair protein

HhH-GPDaa 142–299UCSCHhH-GPD superfamily base excision DNA repair protein

Gene Aliases

HGNC Name

8-oxoguanine DNA glycosylase

HGNC Alias Symbols

HMMH; HOGG1; OGH1; MUTM

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002542.6

p.A329_Q330delFs

c.987_988delTC

Surrounding Variants

1 paper

NM_002542.6

p.Q330*

c.988C>T

1 paper

NM_002542.6

p.R327C

c.979C>T

1 paper

NM_002542.6

p.E331G

c.992A>G

690 papers

NM_002542.6

p.S326C

c.977C>G

NM_016820.4

p.P332A

c.994C>G

NM_016828.3

p.A316_L317Splc

c.948+273C>G

9 papers

NM_002542.6

p.P332A

c.994C>G

1 paper

NM_002542.6

p.P333delFs

c.998delC

1 paper

NM_002542.6

p.R324R

c.972C>G

1 paper

NM_002542.6

p.R324H

c.971G>A

1 paper

NM_002542.6

p.L323L

c.967C>T

1 paper

NM_002542.6

p.D322D

c.966C>T

1 paper

NM_002542.6

p.D322A

c.965A>C

5 papers

NM_002542.6

p.D322N

c.964G>A