Varaico: Literature-Extracted Genetic Variants

PARP2

131 papers

RefSeq Summary

This gene encodes poly(ADP-ribosyl)transferase-like 2 protein, which contains a catalytic domain and is capable of catalyzing a poly(ADP-ribosyl)ation reaction. This protein has a catalytic domain whi...

Pfam Domains

WGRaa 115–195UCSCWGR domain

PARP_regaa 232–362UCSCPoly(ADP-ribose) polymerase, regulatory domain

PARPaa 376–577UCSCPoly(ADP-ribose) polymerase catalytic domain

Gene Aliases

HGNC Name

poly(ADP-ribose) polymerase 2

HGNC Previous Symbol

ADPRTL2

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001042618.2

p.G139R

c.415G>C

Surrounding Variants

1 paper

NM_001042618.2

p.V141Splc

c.421+1G>A

1 paper

NM_001042618.2

p.V141D

c.422T>A

1 paper

NM_001042618.2

p.Q112R

c.335A>G

1 paper

NM_001042618.2

p.Q146*

c.436C>T

1 paper

NM_001042618.2

p.C152Y

c.455G>A

3 papers

NM_001042618.2

p.Y188F

c.563A>T

1 paper

NM_001042618.2

p.Q192*

c.574C>T

1 paper

NM_001042618.2

p.T197S

c.590C>G

1 paper

NM_001042618.2

p.E204fs

c.610_611fs

1 paper

NM_001042618.2

p.E204_E209delFs

c.611_626del16

1 paper

NM_001042618.2

p.K206insFs

c.617_618insG

1 paper

NM_001042618.2

p.K207insFs

c.619_620insG