Varaico: Literature-Extracted Genetic Variants

PGR

1,057 papers

RefSeq Summary

This gene encodes a member of the steroid receptor superfamily. The encoded protein mediates the physiological effects of progesterone, which plays a central role in reproductive events associated wit...

Pfam Domains

Prog_receptoraa 1–564UCSCProgesterone receptor

zf-C4aa 565–634UCSCDouble treble clef zinc finger, C4 type

Hormone_recepaa 704–891UCSCLigand-binding domain of nuclear hormone receptor

Gene Aliases

HGNC Name

progesterone receptor

HGNC Alias Symbols

PR; NR3C3

Papers

RefSeq ID

Protein change

DNA change

1–12 of 604 variants

102 papers

NM_000926.4

p.V660L

c.1978G>T

96 papers

NM_000926.4

p.V660L

c.1978G>C

25 papers

NM_000926.4

p.S344T

c.1031G>C

9 papers

NM_000926.4

p.A15V

c.44C>T

9 papers

NM_000926.4

p.P21A

c.61C>G

8 papers

NM_000926.4

p.Q860K

c.2578C>A

7 papers

NM_000926.4

p.P12A

c.34C>G

7 papers

NM_000926.4

p.H770H

c.2310C>T

6 papers

NM_000926.4

p.L4L

c.12G>A

6 papers

NM_000926.4

p.C361Y

c.1082G>A

5 papers

NM_000926.4

p.L111L

c.331C>T

5 papers

NM_000926.4

p.P186L

c.557C>T