Varaico: Literature-Extracted Genetic Variants

Gene:PKM
Variant:p.S37A

PKM

313 papers

RefSeq Summary

This gene encodes a protein involved in glycolysis. The encoded protein is a pyruvate kinase that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate to ADP, generating ATP and pyruv...

Pfam Domains

PKaa 116–449UCSCPyruvate kinase, barrel domain
PK_Caa 484–602UCSCPyruvate kinase, alpha/beta domain

Gene Aliases

HGNC Name

pyruvate kinase M1/2

HGNC Previous Symbol

PKM2

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
7 papers
NM_002654.6
p.S37A
c.109T>G
Surrounding Variants
3 papers
NM_002654.6
p.S37P
c.109T>C
1 paper
NM_001206798.3
p.I52T
c.155T>C
1 paper
NM_002654.6
p.P38S
c.112C>T
1 paper
NM_002654.6
p.L33L
c.99G>T
1 paper
NM_002654.6
p.L33L
c.99G>C
1 paper
NM_002654.6
p.L33L
c.99G>A
3 papers
NM_002654.6
p.L33R
c.98T>G
1 paper
NM_002654.6
p.T41A
c.121A>G
1 paper
NM_002654.6
p.R32L
c.95G>T
1 paper
NM_002654.6
p.R32C
c.94C>T
3 papers
NM_002654.6
p.C31F
c.92G>T
1 paper
NM_002654.6
p.C31S
c.92G>C
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."