Varaico: Literature-Extracted Genetic Variants

PLK4

171 papers

RefSeq Summary

This gene encodes a member of the polo family of serine/threonine protein kinases. The protein localizes to centrioles, complex microtubule-based structures found in centrosomes, and regulates centrio...

Pfam Domains

Pkinaseaa 12–265UCSCProtein kinase domain

Plk4_PB1aa 591–697UCSCPolo-like Kinase 4 Polo Box 1

Plk4_PB2aa 699–807UCSCPolo-like Kinase 4 Polo Box 2

Gene Aliases

HGNC Name

polo like kinase 4

HGNC Previous Symbol

STK18

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_014264.5

p.L143P

c.428T>C

Surrounding Variants

1 paper

NM_014264.5

p.R146H

c.437G>A

1 paper

NM_014264.5

p.S140A

c.418T>G

4 papers

NM_014264.5

p.M148V

c.442A>G

1 paper

NM_014264.5

p.T138A

c.412A>G

1 paper

NM_014264.5

p.I150T

c.449T>C

9 papers

NM_014264.5

p.D154A

c.461A>C

1 paper

NM_014264.5

p.K162R

c.485A>G

1 paper

NM_014264.5

p.H115P

c.344A>C

1 paper

NM_014264.5

p.R114P

c.341G>C

1 paper

NM_014264.5

p.C172F

c.515G>T

1 paper

NM_014264.5

p.A113A

c.339T>A

1 paper

NM_014264.5

p.T174N

c.521C>A