Varaico: Literature-Extracted Genetic Variants

PPARG

903 papers

RefSeq Summary

This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) subfamily of nuclear receptors. PPARs form heterodimers with retinoid X receptors (RXRs) and these heterodimers regu...

Pfam Domains

PPARgamma_Naa 1–78UCSCPPAR gamma N-terminal region

zf-C4aa 107–175UCSCDouble treble clef zinc finger, C4 type

zf-C4aa 137–205UCSCDouble treble clef zinc finger, C4 type

Hormone_recepaa 269–456UCSCLigand-binding domain of nuclear hormone receptor

Gene Aliases

HGNC Name

peroxisome proliferator activated receptor gamma

HGNC Alias Symbols

PPARG1; PPARG2; NR1C3; PPARgamma

Papers

RefSeq ID

Protein change

DNA change

1–12 of 558 variants

145 papers

NM_138711.6

p.T54I

c.161C>T

31 papers

NM_138711.6

p.P465L

c.1394C>T

27 papers

NM_138711.6

p.T227T

c.681C>G

21 papers

NM_015869.5

p.P12A

c.34C>G

9 papers

NM_138711.6

p.R164W

c.490C>T

8 papers

NM_015869.5

p.R425C

c.1273C>T

7 papers

NM_015869.5

p.Y151C

c.452A>G

7 papers

NM_138711.6

p.L451P

c.1352T>C

6 papers

NM_138711.6

p.E5G

c.14A>G

6 papers

NM_015869.5

p.R212W

c.634C>T

6 papers

NM_015869.5

p.H477H

c.1431C>T

5 papers

NM_015869.5

p.R164W

c.490C>T