Varaico: Literature-Extracted Genetic Variants

Gene:PTGS1
Variant:p.S4S

PTGS1

369 papers

RefSeq Summary

This is one of two genes encoding similar enzymes that catalyze the conversion of arachidonate to prostaglandin. The encoded protein regulates angiogenesis in endothelial cells, and is inhibited by no...

Pfam Domains

An_peroxidaseaa 167–531UCSCAnimal haem peroxidase

Gene Aliases

HGNC Name

prostaglandin-endoperoxide synthase 1

HGNC Alias Symbols

PGHS-1; PTGHS

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_000962.4
p.S4S
c.12T>C
Surrounding Variants
1 paper
NM_000962.4
p.L6S
c.17T>C
1 paper
NM_000962.4
p.L7P
c.20T>C
1 paper
NM_000962.4
p.L7L
c.21C>T
8 papers
NM_000962.4
p.W8R
c.22T>A
9 papers
NM_000962.4
p.W8R
c.22T>C
2 papers
NM_000962.4
p.W8S
c.23G>C
3 papers
NM_000962.4
p.F12_L14del0
c.35_40del6
1 paper
NM_000962.4
p.L13P
c.38T>C
7 papers
NM_000962.4
p.L16del1
c.46_47delCTC
1 paper
NM_000962.4
p.P17T
c.49C>A
85 papers
NM_000962.4
p.P17L
c.50C>T
1 paper
NM_000962.4
p.P18R
c.53C>G
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."