Varaico: Literature-Extracted Genetic Variants

PTGS2

723 papers

RefSeq Summary

Prostaglandin-endoperoxide synthase (PTGS), also known as cyclooxygenase, is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase. There are two isozymes of...

Pfam Domains

An_peroxidaseaa 204–562UCSCAnimal haem peroxidase

Gene Aliases

HGNC Name

prostaglandin-endoperoxide synthase 2

HGNC Previous Name

prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000963.4

p.L517S

c.1550T>C

Surrounding Variants

1 paper

NM_000963.4

p.G519A

c.1556G>C

2 papers

NM_000963.4

p.L520F

c.1558C>T

2 papers

NM_000963.4

p.G522S

c.1564G>A

2 papers

NM_000963.4

p.G512V

c.1535G>T

1 paper

NM_000963.4

p.V511G

c.1532T>G

31 papers

NM_000963.4

p.V511A

c.1532T>C

1 paper

NM_000963.4

p.N523K

c.1569T>G

1 paper

NM_000963.4

p.N523K

c.1569T>A

1 paper

NM_000963.4

p.V511L

c.1531G>C

1 paper

NM_000963.4

p.V509V

c.1527A>C

1 paper

NM_000963.4

p.V509I

c.1525G>A

2 papers

NM_000963.4

p.M508T

c.1523T>C