Varaico: Literature-Extracted Genetic Variants

PTGS2

723 papers

RefSeq Summary

Prostaglandin-endoperoxide synthase (PTGS), also known as cyclooxygenase, is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase. There are two isozymes of...

Pfam Domains

An_peroxidaseaa 204–562UCSCAnimal haem peroxidase

Gene Aliases

HGNC Name

prostaglandin-endoperoxide synthase 2

HGNC Previous Name

prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000963.4

p.F393delFs

c.1177delA

Surrounding Variants

1 paper

NM_000963.4

p.I394T

c.1181T>C

1 paper

NM_000963.4

p.N396S

c.1187A>G

1 paper

NM_000963.4

p.Q391Q

c.1173A>G

1 paper

NM_000963.4

p.N397T

c.1190A>C

2 papers

NM_000963.4

p.S398A

c.1192T>G

1 paper

NM_000963.4

p.Y390N

c.1168T>A

2 papers

NM_000963.4

p.N389T

c.1166A>C

55 papers

NM_000963.4

p.I399V

c.1195A>G

1 paper

NM_000963.4

p.N389D

c.1165A>G

1 paper

NM_000963.4

p.I399T

c.1196T>C

1 paper

NM_000963.4

p.Q386R

c.1157A>G

1 paper

NM_000963.4

p.H384R

c.1151A>G