Varaico: Literature-Extracted Genetic Variants

PTK6

95 papers

RefSeq Summary

The protein encoded by this gene is a cytoplasmic nonreceptor protein kinase which may function as an intracellular signal transducer in epithelial tissues. Overexpression of this gene in mammary epit...

Pfam Domains

SH3_1aa 14–64UCSCSH3 domain

SH2aa 78–155UCSCSH2 domain

PK_Tyr_Ser-Thraa 191–441UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

protein tyrosine kinase 6

HGNC Previous Name

PTK6 protein tyrosine kinase 6

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_005975.4

p.F434L

c.1302C>G

Surrounding Variants

1 paper

NM_005975.4

p.F434L

c.1302C>A

1 paper

NM_005975.4

p.F434L

c.1300T>C

1 paper

NM_005975.4

p.E429K

c.1285G>A

1 paper

NM_005975.4

p.P428A

c.1282C>G

7 papers

NM_005975.4

p.Y447F

c.1340A>T

1 paper

NM_005975.4

p.E448Q

c.1342G>C

3 papers

NM_005975.4

p.P450L

c.1349C>T

1 paper

NM_005975.4

p.S415N

c.1244G>A

1 paper

NM_005975.4

p.E411D

c.1233G>T

1 paper

NM_005975.4

p.E411D

c.1233G>C

1 paper

NM_005975.4

p.P407T

c.1219C>A

1 paper

NM_005975.4

p.R405C

c.1213C>T