Varaico: Literature-Extracted Genetic Variants

PTK6

95 papers

RefSeq Summary

The protein encoded by this gene is a cytoplasmic nonreceptor protein kinase which may function as an intracellular signal transducer in epithelial tissues. Overexpression of this gene in mammary epit...

Pfam Domains

SH3_1aa 14–64UCSCSH3 domain

SH2aa 78–155UCSCSH2 domain

PK_Tyr_Ser-Thraa 191–441UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

protein tyrosine kinase 6

HGNC Previous Name

PTK6 protein tyrosine kinase 6

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_005975.4

p.V253M

c.757G>A

Surrounding Variants

1 paper

NM_005975.4

p.A252V

c.755C>T

1 paper

NM_005975.4

p.V256L

c.766G>C

1 paper

NM_005975.4

p.G257A

c.770G>C

1 paper

NM_005975.4

p.V260E

c.779T>A

1 paper

NM_005975.4

p.R243W

c.727C>T

1 paper

NM_005975.4

p.D224Splc

c.670+385C>G

9 papers

NM_005975.4

p.K219M

c.656A>T

1 paper

NM_005975.4

p.K219R

c.656A>G

1 paper

NM_005975.4

p.I218F

c.652A>T

1 paper

NM_005975.4

p.K211*

c.631A>T

1 paper

NM_005975.4

p.K211E

c.631A>G

1 paper

NM_005975.4

p.W210C

c.630G>T