Varaico: Literature-Extracted Genetic Variants

PTPN21

110 papers

RefSeq Summary

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell gro...

Pfam Domains

FERM_Naa 27–90UCSCFERM N-terminal domain

FERM_Maa 106–222UCSCFERM central domain

FERM_Caa 226–312UCSCFERM C-terminal PH-like domain

Y_phosphataseaa 921–1166UCSCProtein-tyrosine phosphatase

Gene Aliases

HGNC Name

protein tyrosine phosphatase non-receptor type 21

HGNC Alias Symbols

PTPD1; PTPRL10

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_007039.4

p.E1067D

c.3201A>C

Surrounding Variants

2 papers

NM_007039.4

p.E1067D

c.3201A>T

1 paper

NM_007039.4

p.D1064Y

c.3190G>T

1 paper

NM_007039.4

p.F1032S

c.3095T>C

1 paper

NM_007039.4

p.A998S

c.2992G>T

1 paper

NM_007039.4

p.E1083A

c.3248A>C

1 paper

NM_007039.4

p.R1089H

c.3266G>A

3 papers

NM_007039.4

p.P1102L

c.3305C>T

6 papers

NM_007039.4

p.C1108S

c.3322T>A

6 papers

NM_007039.4

p.C1108S

c.3323G>C

1 paper

NM_007039.4

p.A1126T

c.3376G>A

1 paper

NM_007039.4

p.N1131S

c.3392A>G

1 paper

NM_007039.4

p.V1139M

c.3415G>A