Varaico: Literature-Extracted Genetic Variants

PTPRC

1,024 papers

RefSeq Summary

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell gro...

Pfam Domains

PTP_Naa 7–32UCSCProtein tyrosine phosphatase N terminal

CD45aa 237–295UCSCLeukocyte receptor CD45

fn3aa 483–568UCSCFibronectin type III domain

Y_phosphataseaa 677–911UCSCProtein-tyrosine phosphatase

Y_phosphataseaa 968–1227UCSCProtein-tyrosine phosphatase

Gene Aliases

HGNC Name

protein tyrosine phosphatase receptor type C

HGNC Previous Symbol

CD45

Papers

RefSeq ID

Protein change

DNA change

1–12 of 473 variants

17 papers

NM_002838.5

p.S46S

c.138A>G

8 papers

NM_002838.5

p.P301S

c.901C>T

7 papers

NM_002838.5

p.T193A

c.577A>G

6 papers

NM_002838.5

p.D123H

c.367G>C

6 papers

NM_002838.5

p.P301L

c.902C>T

6 papers

NM_002838.5

p.Q1081Q

c.3243A>G

4 papers

NM_002838.5

p.H570Q

c.1710T>A

4 papers

NM_002838.5

p.H570Q

c.1710T>G

4 papers

NM_002838.5

p.S573A

c.1717T>G

3 papers

NM_002838.5

p.G13D

c.38G>A

3 papers

NM_002838.5

p.V23V

c.69G>C

3 papers

NM_002838.5

p.P59P

c.177C>G