Varaico: Literature-Extracted Genetic Variants

RASSF1

115 papers

RefSeq Summary

This gene encodes a protein similar to the RAS effector proteins. Loss or altered expression of this gene has been associated with the pathogenesis of a variety of cancers, which suggests the tumor su...

Pfam Domains

C1_1aa 52–108UCSCPhorbol esters/diacylglycerol binding domain (C1 domain)

RAaa 203–292UCSCRas association (RalGDS/AF-6) domain

Nore1-SARAHaa 299–338UCSCNovel Ras effector 1 C-terminal SARAH (Sav/Rassf/Hpo) domain

Gene Aliases

HGNC Name

Ras association domain family member 1

HGNC Alias Symbols

NORE2A; REH3P21; RDA32; 123F2

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_007182.5

p.S131A

c.391T>G

Surrounding Variants

13 papers

NM_007182.5

p.S131F

c.392C>T

NM_170713.3

p.S61F

c.182C>T

38 papers

NM_007182.5

p.A133S

c.397G>T

1 paper

NM_007182.5

p.P128A

c.382C>G

1 paper

NM_007182.5

p.I135T

c.404T>C

1 paper

NM_170713.3

p.V53L

c.157G>T

NM_007182.5

p.V123L

c.367G>T

1 paper

NM_170713.3

p.V53L

c.157G>C

NM_007182.5

p.V123L

c.367G>C

2 papers

NM_007182.5

p.A144P

c.430G>C

1 paper

NM_007182.5

p.N147D

c.439A>G

1 paper

NM_007182.5

p.L150P

c.449T>C

1 paper

NM_007182.5

p.D157G

c.470A>G

1 paper

NM_007182.5

p.P183P

c.549C>A

1 paper

NM_007182.5

p.S184A

c.550T>G