Varaico: Literature-Extracted Genetic Variants

Gene:RBBP6
Variant:p.R536*

RBBP6

216 papers

RefSeq Summary

The retinoblastoma tumor suppressor (pRB) protein binds with many other proteins. In various human cancers, pRB suppresses cellular proliferation and is inactivated. Cell cycle-dependent phosphorylati...

Pfam Domains

DWNNaa 4–76UCSCDWNN domain
zf-CCHC_2aa 156–176UCSCZinc knuckle
U-boxaa 253–327UCSCU-box domain

Gene Aliases

HGNC Name

RB binding protein 6, ubiquitin ligase

HGNC Alias Symbols

P2P-R; PACT; SNAMA

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_006910.5
p.R536*
c.1606C>T
Surrounding Variants
1 paper
NM_006910.5
p.R541T
c.1622G>C
1 paper
NM_006910.5
p.R544K
c.1631G>A
25 papers
NM_006910.5
p.G547S
c.1639G>A
1 paper
NM_006910.5
p.P548L
c.1643C>T
1 paper
NM_006910.5
p.A552G
c.1655C>G
1 paper
NM_006910.5
p.V555G
c.1664T>G
1 paper
NM_006910.5
p.G577_Q586del10
c.1729_1757del30
1 paper
NM_006910.5
p.P592_P593delFs
c.1776_1777delAC
1 paper
NM_006910.5
p.P593L
c.1778C>T
2 papers
NM_006910.5
p.A595T
c.1783G>A
1 paper
NM_006910.5
p.G603W
c.1807G>T
1 paper
NM_006910.5
p.P608S
c.1822C>T
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