Varaico: Literature-Extracted Genetic Variants

RET

5,388 papers

RefSeq Summary

This gene encodes a transmembrane receptor and member of the tyrosine protein kinase family of proteins. Binding of ligands such as GDNF (glial cell-line derived neurotrophic factor) and other related...

Pfam Domains

RET_CLD1aa 29–154UCSCRET Cadherin like domain 1

Cadherinaa 172–261UCSCCadherin domain

RET_CLD3aa 265–379UCSCRET Cadherin like domain 3

RET_CLD4aa 282–375UCSCRET Cadherin like domain 4

RET_CLD4aa 404–507UCSCRET Cadherin like domain 4

RET_CRDaa 518–620UCSCRET, Cysteine Rich Domain

Gene Aliases

HGNC Name

ret proto-oncogene

HGNC Previous Symbols

HSCR1; MEN2A; MTC1; MEN2B

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

59 papers

NM_020975.6

p.S904C

c.2711C>G

Surrounding Variants

2 papers

NM_020975.6

p.S904Y

c.2711C>A

66 papers

NM_020975.6

p.S904F

c.2711C>T

1 paper

NM_020975.6

p.S904delins

c.2711_2712delinsTG

64 papers

NM_020975.6

p.S904S

c.2712C>G

1 paper

NM_020975.6

p.S904S

c.2712C>T

1 paper

NM_020975.6

p.S904T

c.2710T>A

1 paper

NM_020975.6

p.S904P

c.2710T>C

4 papers

NM_020975.6

p.S904A

c.2710T>G

1 paper

NM_020975.6

p.D903G

c.2708A>G

27 papers

NM_020975.6

p.Y905F

c.2714A>T

1 paper

NM_020975.6

p.D903V

c.2708A>T

3 papers

NM_020975.6

p.D903N

c.2707G>A