Varaico: Literature-Extracted Genetic Variants

RIGI

518 papers

RefSeq Summary

DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases which are implicated in a number of cellular processes involving RNA binding and alteration o...

Pfam Domains

CARD_2aa 1–93UCSCCaspase recruitment domain

DEADaa 41–217UCSCDEAD/DEAH box helicase

CARD_2aa 99–190UCSCCaspase recruitment domain

RIG-I_Caa 254–399UCSCRIG-I receptor C-terminal domain

Helicase_Caa 406–531UCSCHelicase conserved C-terminal domain

RIG-I_C-RDaa 603–720UCSCC-terminal domain of RIG-I

Gene Aliases

HGNC Name

RNA sensor RIG-I

HGNC Previous Symbol

DDX58

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_014314.4

p.L185L

c.553C>T

Surrounding Variants

9 papers

NM_014314.4

p.S183I

c.548G>T

1 paper

NM_014314.4

p.F182V

c.544T>G

2 papers

NM_014314.4

p.K181R

c.542A>G

2 papers

NM_014314.4

p.K190R

c.569A>G

1 paper

NM_014314.4

p.K177R

c.530A>G

1 paper

NM_014314.4

p.E176D

c.528G>T

1 paper

NM_014314.4

p.E176D

c.528G>C

1 paper

NM_014314.4

p.L173R

c.518T>G

12 papers

NM_014314.4

p.K172R

c.515A>G

2 papers

NM_014314.4

p.K169R

c.506A>G

1 paper

NM_014314.4

p.E165V

c.494A>T

3 papers

NM_014314.4

p.K164R

c.491A>G