Varaico: Literature-Extracted Genetic Variants

SGK1

249 papers

RefSeq Summary

This gene encodes a serine/threonine protein kinase that plays an important role in cellular stress response. This kinase activates certain potassium, sodium, and chloride channels, suggesting an invo...

Pfam Domains

Pkinaseaa 98–355UCSCProtein kinase domain

Pkinase_Caa 376–423UCSCProtein kinase C terminal domain

Gene Aliases

HGNC Name

serum/glucocorticoid regulated kinase 1

HGNC Previous Name

serum/glucocorticoid regulated kinase

Papers

RefSeq ID

Protein change

DNA change

1–12 of 336 variants

6 papers

NM_001143676.3

p.M32L

c.94A>T

6 papers

NM_001143676.3

p.M32L

c.94A>C

6 papers

NM_001143676.3

p.A121V

c.362C>T

6 papers

NM_001143676.3

p.H146Splc

c.437+1G>A

6 papers

NM_001143676.3

p.E162D

c.486G>C

5 papers

NM_001143676.3

p.M32V

c.94A>G

5 papers

NM_001143676.3

p.C86S

c.256T>A

5 papers

NM_001143676.3

p.A121G

c.362C>G

5 papers

NM_001143676.3

p.E162D

c.486G>T

3 papers

NM_001143676.3

p.Q66E

c.196C>G

3 papers

NM_001143676.3

p.H72R

c.215A>G

3 papers

NM_001143676.3

p.Q125*

c.373C>T