Varaico: Literature-Extracted Genetic Variants

Gene:SIRT2
Variant:p.L172M

SIRT2

150 papers

RefSeq Summary

This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes...

Pfam Domains

SIR2aa 84–268UCSCSir2 family

Gene Aliases

HGNC Name

sirtuin 2

HGNC Previous Symbol

SIR2L

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_012237.4
p.L172M
c.514C>A
Surrounding Variants
1 paper
NM_012237.4
p.E173D
c.519G>T
1 paper
NM_012237.4
p.E173D
c.519G>C
1 paper
NM_012237.4
p.D170A
c.509A>C
1 paper
NM_012237.4
p.D170N
c.508G>A
1 paper
NM_012237.4
p.G177W
c.529G>T
2 papers
NM_012237.4
p.A186V
c.557C>T
28 papers
NM_012237.4
p.H187Y
c.559C>T
2 papers
NM_012237.4
p.F190V
c.568T>G
1 paper
NM_012237.4
p.Y191D
c.571T>G
1 paper
NM_012237.4
p.E203G
c.608A>G
1 paper
NM_012237.4
p.P205S
c.613C>T
1 paper
NM_012237.4
p.L206R
c.617T>G
UCSC Genome Browser·Imprint·Privacy·Terms·Feedback·Email Updates·

Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."