Varaico: Literature-Extracted Genetic Variants

SLCO1B1

1,357 papers

RefSeq Summary

This gene encodes a liver-specific member of the organic anion transporter family. The encoded protein is a transmembrane receptor that mediates the sodium-independent uptake of numerous endogenous co...

Pfam Domains

OATPaa 29–621UCSCOrganic Anion Transporter Polypeptide (OATP) family

Kazal_2aa 460–506UCSCKazal-type serine protease inhibitor domain

Gene Aliases

HGNC Name

solute carrier organic anion transporter family member 1B1

HGNC Previous Symbol

SLC21A6

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_006446.5

p.V158A

c.473T>C

Surrounding Variants

2 papers

NM_006446.5

p.V158M

c.472G>A

20 papers

NM_006446.5

p.E156G

c.467A>G

1 paper

NM_006446.5

p.G161S

c.481G>A

2 papers

NM_006446.5

p.P155H

c.464C>A

11 papers

NM_006446.5

p.G161Splc

c.481+1G>T

127 papers

NM_006446.5

p.P155T

c.463C>A

1 paper

NM_006446.5

p.P155S

c.463C>T

1 paper

NM_006446.5

p.S154S

c.462A>T

1 paper

NM_006446.5

p.A153V

c.458C>T

1 paper

NM_006446.5

p.A153T

c.457G>A

12 papers

NM_006446.5

p.R152K

c.455G>A

1 paper

NM_006446.5

p.R152T

c.455G>C