Varaico: Literature-Extracted Genetic Variants

SLCO1B1

1,357 papers

RefSeq Summary

This gene encodes a liver-specific member of the organic anion transporter family. The encoded protein is a transmembrane receptor that mediates the sodium-independent uptake of numerous endogenous co...

Pfam Domains

OATPaa 29–621UCSCOrganic Anion Transporter Polypeptide (OATP) family

Kazal_2aa 460–506UCSCKazal-type serine protease inhibitor domain

Gene Aliases

HGNC Name

solute carrier organic anion transporter family member 1B1

HGNC Previous Symbol

SLC21A6

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_006446.5

p.I172T

c.515T>C

Surrounding Variants

1 paper

NM_006446.5

p.I172I

c.516A>C

1 paper

NM_006446.5

p.W171*

c.513G>A

1 paper

NM_006446.5

p.Y173C

c.518A>G

1 paper

NM_006446.5

p.W171*

c.512G>A

1 paper

NM_006446.5

p.W171G

c.511T>G

4 papers

NM_006446.5

p.V174E

c.521T>A

891 papers

NM_006446.5

p.V174A

c.521T>C

2 papers

NM_006446.5

p.M170T

c.509T>C

1 paper

NM_006446.5

p.M170L

c.508A>C

1 paper

NM_006446.5

p.M170L

c.508A>T

2 papers

NM_006446.5

p.V174V

c.522G>C

1 paper

NM_006446.5

p.M176delFs

c.526delA